The Lancet, one of the "four journals of clinical medicine", published online the phase results of the clinical research on drug weight loss at West China Hospital of Sichuan University on December 9, 2021. The research systematically estimated the efficacy and safety of different weight loss drugs in the weight loss treatment of overweight and obese adults.
The two first authors are Qingyang Shi of the Department of Guideline and Rapid Recommendation, Cochrane China Center, MAGIC China Center, Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University and Yang Wang, a master student of the Department of Endocrinology and Metabolism, West China Hospital. The corresponding author is Dr. Sheyu Li of the Department of Endocrinology and Metabolism and Department of Guideline and Rapid Recommendation, Cochrane China Center, MAGIC China Center, Chinese Evidence-Based Medicine Center, West China Hospital.
Pharmacotherapy provides an option for adults with overweight and obesity to reduce their bodyweight if lifestyle modifications fail. This paper summarized the latest evidence for the benefits and harms of weight-lowering drugs so as to provide reference for the treatment options of people suffering from weight problems all over the world.
Invited by The Lancet's editorial office, Prof. CW Le Roux of the University College Doblin in Ireland spoke highly of the impact of the study on clinical practice. Before its official publication, the study has been cited by many high-level journals such as The Lancet, and its preprint has steadily ranked among the top 10 in many fields such as obesity and public health. Clinicians, Methodists and graduate students from Evidence Ecology Foundation of Norway, McMaster University of Canada, Tianjin University of Traditional Chinese Medicine, Lanzhou University, Peking University, Xi'an Jiaotong University, West China School of Public Health of Sichuan University and so forth participated in the study. In addition, the study received strong support from the guideline expert group composed of more than 20 clinical experts engaged in obesity diagnosis and treatment from all over the country as well as the 1.3.5 Project for Disciplines of Excellence, West China Hospital of Sichuan University. This is another landmark achievement of the Department of Guideline and Rapid Recommendation, Cochrane China Center, MAGIC China Center, Chinese Evidence-Based Medicine Center, West China Hospital regarding the clinical practice guide for diabetes since May 2021.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01640-8/fulltext
